Objective: To evaluate the warefront aberrations changes in astigmatic eyes by being fitted with hydrogel soft contact lenses.
Methods: 41 eyes of 22 patients with astigmatism were fitted with hydrogel soft contact lenses. Higher order aberrations (HOA) were quantified with COAS wavefront sensor（Complete Ophthalmic Analysis System，COAS， WaveFront Sciences, Inc). 3^rd to 6^th order RMS values, coma and spherical aberrations at 3 and 5mmpupil were compared before and after soft contact lenses were inserted. Paired sample t–test was used to analyze the data in SPSS 13.0 software.
Results: RMS of 3^rd to 6^th and total higher order aberrations were significantly increased after inserting contact lens at 3 and5mm pupil. Horizontal coma and spherical aberrations were slightly decreased after wearing soft contact lens at 3mm pupil. Vertical coma at 3 and 5mm pupil, horizontal coma and spherical aberration at5mmpupil were significantly increased.
Conclusions: hydrogel soft contact lenses corrected astigmatic refractive error, while induced significant increase in higher order RMS and vertical coma both at 3 and5mmpupil.  Horizontal coma and spherical aberration were similar at small pupil, while the increases were statistically significant at 5mmpupil.